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Table 2: Mean FA of clusters with statistically significant differences between patients with ALS with T1 MTC hyperintense signal and those without it and controls^a
Patients with ALS Controls
MT Hyperintensity No MT Hyperintensity
Entire CST 0.403 (0.024) 0.432 (0.022) 0.454 (0.024)
CST including internal capsule 0.373 (0.024) 0.411 (0.021) 0.431 (0.024)
Middle cerebellar peduncles 0.435 (0.020) 0.464 (0.019) 0.480 (0.020)
Pons 0.414 (0.014) 0.427 (0.014) 0.445 (0.015)
Entire CC 0.580 (0.018) 0.569 (0.018) 0.619 (0.019)
Genu CC 0.517 (0.022) 0.499 (0.022) 0.549 (0.023)
Body CC 0.530 (0.014) 0.524 (0.014) 0.584 (0.015)
Anterior body CC 0.532 (0.013) 0.514 (0.013) 0.571 (0.014)
Posterior body CC 0.528 (0.015) 0.536 (0.015) 0.602 (0.016)
Splenium CC 0.679 (0.015) 0.665 (0.015) 0.706 (0.015)
Temporal white matter 0.268 (0.013) 0.245 (0.012) 0.281 (0.013)
Parietal white matter 0.236 (0.016) 0.212 (0.015) 0.255 (0.016)
Frontal white matter 0.243 (0.014) 0.234 (0.013) 0.259 (0.014)


↵a All P values <.05. Numbers in parentheses are SDs.