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Table 1: WMA assessment at conventional MRI
Characteristics Score 1 Score 2 Score 3
White matter signal abnormality Normal Focal regions Multiple regions
(<2 regions per hemisphere) (>2 regions)
34/70 (48.6%) 15/70 (21.4%) 21/70 (30.0%)
White matter volume loss Normal Mild reduction with increased ventricular size (EI = 0.3–0.36) Marked reduction with increased ventricular size (EI > 0.36)
61/70 (87.1%) 9/70 (12.9%) 0/70 (0%)
Cystic abnormalities Normal <2-mm single focal cyst Multiple cysts or a single larger (>2 mm) focal cyst
66/70 (94.3%) 0/70 (0%) 4/70 (5.7%)
Ventricular dilation Normal Mild-moderate enlargement of the frontal, temporal, and occipital horns More global enlargement of the frontal, temporal, and occipital horns
57/70 (81.4%) 12/70 (17.2%) 1/70 (1.4%)
Thinning of the corpus callosum Normal Focal thinning in the corpus callosum Global thinning across the entire corpus callosum
54/70 (77.2%) 15/70 (21.4%) 1/70 (1.4%)

Note:—EI indicates Evans Index.