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Table 1: 
Demographic characteristics of subjects
Control(n = 15)PD(n = 15)PDD(n = 15)P Value(Control vs PD)P Value(Control vs PDD)P Value(PD vs PDD)
Sex, male/female6:99:68:7NSNSNS
Age in years, (mean) (SD)69.5 (6.9)69.8 (5.9)71.3 (5.6)NSNSNS
Disease duration in months (mean) (SD)NA70.6 (58)139.0 (96.5)NANA<.05
Hoehn and Yahr stage (SD)02.3 (1.3)3.0 (0.7)NANA<.05
MMSE (SD)28.526.1 (3.2)20.2 (4.0)NS<.01<.01
UPDRS-III score (SD)NA19.0 (12.0)27.1 (9.9)NANA<.05
Levodopa dosage (mg/day) (median) (SD)0409.1 (280.3)687.0 (126.0)NANA<.05
  • Note:—NA indicates not applicable; NS, not significant (P > .05).