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Table 1: Patient characteristics
RRMS (n = 20/47) CIS (n = 27/47)
RRMS Control MCIS Control PCISWOE Control PCISWE Control
No. of subjects 20 20 9 9 9 9 9 9
Mean age at disease onset (yr) 14.23 NA 12.99 NA 15.06 NA 9.37 NA
Range 6.6–16.5 4.1–17.4 13.9–18 2.6–15.3 
Mean age at the time of MRI (yr) 15.92 15.925 13.58 13.58 15.58 15.52 9.74 9.4
Range 8.4–18 7.7–18 4.1–18 4–17.5 14.5–18 13–17 2.6–15.8 2–15
Female sex (%) 75% 77.78% 66.67% 55.56% 
Race 
    White 75% 77.78% 66.67% 44.44% 
    Hispanic 05% 00% 22.22% 11.11% 
    American black 15% 11.11% 11.11% 22.22% 
    Asian 05% 11.11% 00% 11.11% 
Mean disease duration from 1st Sx to MRI analyzed 2.11 yr NA 0.27 yr NA 0.37 yr NA 0.1125 yr NA
Mean EDSS 1.625 NA 1.83 NA 1.38 NA 2.6 NA
No. of patients on DMT at the time of MRI 15/20 NA 00/10 NA 02/09 NA 00/10 NA
    Avonex^{^a} 05/15 NA 00/10 NA 00/09 NA 00/10 NA
    Rebif^{^a} 04/15 NA 00/10 NA 01/09 NA 00/10 NA
    Copaxone^{^b} 04/15 NA 00/10 NA 01/09 NA 00/10 NA
    Multiple drugs 02/15 NA 00/10 NA 00/09 NA 00/10 NA
No. of patients on monthly steroids 05/20 NA 00/10 NA 00/09 NA 00/10 NA
No. of patients on steroids within 1 month of MRI 05/20 NA 06/10 NA 02/09 NA 10/10 NA
Note:—NA indicates not applicable; EDSS, Expanded Disability Status Scale; Sx = symptom; DMT, disease-modifying treatment.
↵a Interferonβ-1a.
↵b Glatiramer acetate.