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Table 3: Clinical and DTI parameters of patients with MS without active lesions
RRMS (n = 12) PPMS (n = 4) SPMS (n = 4) Progressive MS (n = 8)
EDSS (median [min;max]) 3.0 [0;8] 6.75 [4;8] 6.5 [6.5;7.5] 6.5 [4;8]
Pyramidal FS (median [min;max])^{^a} 2 [0;5] 4 [2;5] 4 [4;4] 4 [2;5]
Sensory FS (median [min;max])^{^a} 2 [0;3] 3 [1;4] 3.5 [3;4] 3 [1;4]
FA (mean) 0.56 ± 0.03 0.53 ± 0.04 0.49 ± 0.03 0.51 ± 0.04
MD (10⁻³ mm²/s) (mean) 1.36 ± 0.15 1.40 ± 0.26 1.52 ± 0.25 1.46 ± 0.25
Ratio (mean)^{^b} 2.29 ± 0.26 2.13 ± 0.20 1.99 ± 0.18 2.06 ± 0.19
Note:—min indicates minimum; max, maximum; FS, functional score; RRMS, relapsing-remitting MS; SPMS, secondary-progressive MS; PPMS, primary-progressive MS; EDSS, Expanded Disability Status Scale.
↵a 0–6.
↵b Ratios of aD and rD

	RRMS (n = 12)	PPMS (n = 4)	SPMS (n = 4)	Progressive MS (n = 8)
EDSS (median [min;max])	3.0 [0;8]	6.75 [4;8]	6.5 [6.5;7.5]	6.5 [4;8]
Pyramidal FS (median [min;max])^{^a}	2 [0;5]	4 [2;5]	4 [4;4]	4 [2;5]
Sensory FS (median [min;max])^{^a}	2 [0;3]	3 [1;4]	3.5 [3;4]	3 [1;4]
FA (mean)	0.56 ± 0.03	0.53 ± 0.04	0.49 ± 0.03	0.51 ± 0.04
MD (10⁻³ mm²/s) (mean)	1.36 ± 0.15	1.40 ± 0.26	1.52 ± 0.25	1.46 ± 0.25
Ratio (mean)^{^b}	2.29 ± 0.26	2.13 ± 0.20	1.99 ± 0.18	2.06 ± 0.19