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Table 2: Association between measures of WMH and cognitive function using MoCA cutoffs for cognitive deficit as originally published and as established in our cohort
Normal (MoCA>25) Deficit (MoCA≤25) P Value Normal (MoCA>19) Deficit (MoCA≤19) P Value
N (%) 210 (41.2) 300 (58.8) 441 (86.5) 69 (13.5) 
Visual Scale^{^a} 
Absent (%) 103 117 0.050 199 21 0.001
Minimal (%) 92 143 204 31 
Moderate (%) 12 30 29 13 
Advanced (%) 3 10 9 4 
Automated Volume^{^b} (mL), median (range) 0.815 (0.14–39.64) 0.95 (0.13–83.18) 0.014 0.90 (0.13–83.18) 1.05 (0.14–45.48) 0.091
↵a Pearson χ-square
↵b Mann-Whitney U test

	Normal (MoCA>25)	Deficit (MoCA≤25)	P Value	Normal (MoCA>19)	Deficit (MoCA≤19)	P Value
N (%)	210 (41.2)	300 (58.8)		441 (86.5)	69 (13.5)
Visual Scale^{^a}
Absent (%)	103	117	0.050	199	21	0.001
Minimal (%)	92	143		204	31
Moderate (%)	12	30		29	13
Advanced (%)	3	10		9	4
Automated Volume^{^b} (mL), median (range)	0.815 (0.14–39.64)	0.95 (0.13–83.18)	0.014	0.90 (0.13–83.18)	1.05 (0.14–45.48)	0.091