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Table 1: Mean values of DCE-MR imaging indices, serum MMP-9 expression, and edema volume for different stages of NCC
NCC Stages rCBF rCBV k_ep (min⁻¹) K^trans (min⁻¹) v_e MMP-9 (ng/mL) Edema (cc)
Colloidal 3.53 ± 1.05 2.91 ± 1.67 1.44 ± 0.48 0.16 ± 0.11 0.11 ± 0.08 796.4 ± 273.7 18.1 ± 11.5
Granular-nodular 3.02 ± 1.36 1.94 ± 0.94 0.96 ± 0.22 0.10 ± 0.07 0.10 ± 0.07 569.3 ± 295.6 4.3 ± 1.9
Calcified 1.28 ± 0.23 1.21 ± 0.28 0.63 ± 0.36 0.02 ± 0.01 0.04 ± 0.04 214.3 ± 77.1 −
^*P value <.001 <.001 <.001 <.001 .005 <.001 <.001^*
Note:—Min indicates minutes.
↵* Showing statistical significance on the Student t test. Other values are from 1-way analysis of variance.

NCC Stages	rCBF	rCBV	k_ep (min⁻¹)	K^trans (min⁻¹)	v_e	MMP-9 (ng/mL)	Edema (cc)
Colloidal	3.53 ± 1.05	2.91 ± 1.67	1.44 ± 0.48	0.16 ± 0.11	0.11 ± 0.08	796.4 ± 273.7	18.1 ± 11.5
Granular-nodular	3.02 ± 1.36	1.94 ± 0.94	0.96 ± 0.22	0.10 ± 0.07	0.10 ± 0.07	569.3 ± 295.6	4.3 ± 1.9
Calcified	1.28 ± 0.23	1.21 ± 0.28	0.63 ± 0.36	0.02 ± 0.01	0.04 ± 0.04	214.3 ± 77.1	−
^*P value	<.001	<.001	<.001	<.001	.005	<.001	<.001^*