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Review of published reports about recanalization and outcome of patients with acute vertebrobasilar occlusions treated with thrombolysis and/or thrombectomy
Reference Treatment No. of Patients TICI 2–3 90-Day mRS 0–2 Mortality ICH
Sairanen et al¹⁰ IVT 116 64.8% 26% 41.4% 15.7%
Lindsberg and Mattle⁸ IVT 76 53% 22% 52.6% 11%
Lindsberg and Mattle⁸ IAT 344 65% 24% 55.2% 8%
Schulte-Altedorneburg et al⁹ IAT 180 55% 26.5% 43% 32%
Lutsep et al¹⁹ IVT ± Merci ± IAT 27 78% 33% 44% 19%
Pfefferkorn et al²⁰ IVT ± Merci ± TA 26 85% 38% 31% 8%
Miteff et al¹⁸ SR ± IAT ± TA 10 100% 20% 33.3% 10%
Costalat et al¹⁶ IVT + SR 16 81% 44% 25% 6.2%
Andersson et al²² Merci ± IAT ± SR 28 96% 57% 21% 10.7%
Mordasini et al²¹ IVT ± IAT ± TA ± SR 14 100% 28.6% 35.7% 21.4%
Our group SR 18 94.4% 50% 22.2% 5.5%
Note:—IAT indicates intra-arterial thrombolysis; ICH, intracranial hemorrhage; IVT, intravenous thrombolysis; Merci, Merci retriever; TA, thromboaspiration.