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Table 2: Comparison of CBF in patients with NF-1 and control subjects by anatomic location and vascular territories
Structure Control CBF, mL/100 mg per minute (n = 14) NF-1 CBF, mL/100 mg per minute (n = 14) Mann-Whitney P Value
ACA territory 
    Anterior cingulate gyrus 71 ± 7 61 ± 8 ^a.001
    Medial frontal cortex 65 ± 7 56 ± 9 ^a.004
    Anterior caudate nucleus 57 ± 9 51 ± 4 .013
ACA-MCA borderzone 
    Centrum semiovale 28 ± 5 22 ± 4 ^a.004
MCA territory 
    Frontal operculum 68 ± 8 60 ± 8 .013
    Globus pallidus 50 ± 6 44 ± 6 .012
MCA-PCA borderzone 
    Parietal cortex 65 ± 9 55 ± 9 .008
    Superomedial temporal cortex 67 ± 9 60 ± 8 .012
    Temporo-occipital cortex 64 ± 10 51 ± 8 ^a.002
Anterior choroidal–PcomA–PCA 
    Thalamus 55 ± 10 44 ± 8 ^a.001
PCA territory 
    Posterior cingulate gyrus 70 ± 13 57 ± 8 ^a.002
    Occipital cortex 61 ± 13 45 ± 10 ^a.001
Note:—ACA indicates anterior cerebral artery; PCA, posterior cerebral artery; PcomA, posterior communicating artery.
↵a Significant at ≤.004.