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Table 2: Definite vs no or questionable histologic damage to carotid arteries under various conditions of catheter testing in vivo
Condition Tested Definite Damage (%) No/Questionable Damage (%) Odds Ratio 95% CI P Value^*
Arterial stasis (n = 24) 4 96 3.0 0.36–137 .44
Normal flow (n = 70) 11 89
Current ≤300 mA (n = 58) 0 100 0 0–0.21 .0001
Current > 300 mA (n = 36) 25 75
Activations ≤1 min (n = 52) 6 94 0.37 0.056–1.9 .29
Activations > 1 min (n = 42) 14 86
Work ≤100 J (n = 68) 3 97 0.082 0.008–0.5 .0015
Work >100 J (n = 26) 27 73
Saline drip ≤2 mL/min (n = 39) 15 85 3.2 0.61–21 .16
Saline drip > 2 mL/min (n = 55) 5 95
≤5°C catheter tip coil temperature rise (n = 36) 0 100 0 0–0.36 .0022
> 5°C temperature rise (n = 29) 24 76
MR and x-ray guidance (n = 45) 11 88 1.9 0.35–13 .47
X-ray guidance only (n = 49) 6 94
CI indicates confidence interval; J, Joules; mA, milliamperes.
Note:—Definite damage denotes a histologic score of 2; questionable damage, histologic score of 1; and no damage, histologic score of 0.
↵* P value = 2-tailed Fisher exact test.