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Table 4: Perinatal variables and grade of global brain abnormality in VPT infants
Variables Global Brain Abnormality P Value
Normal (Score 0–3) n = 18 Mild (Score 4–7) n = 45 Moderate (Score 8–11) n = 21 Severe (Score ≥12) n = 13
Gestation at birth (weeks) 27.4 (1.5) 26.9 (1.6) 25.9 (1.7) 26.2 (2.5) .03
Birth weight (g) 1067 (222) 992 (235) 789 (185) 897 (305) .002
Birth weight < −2 SD 1 (6%) 3 (7%) 1 (5%) 1 (8%) .99
Male sex 9 (50%) 22 (49%) 6 (29%) 6 (46%) .43
Singleton 9 (50%) 13 (29%) 6 (29%) 5 (39%) .40
Critical Risk Index for Babies score 1 [1–4] 2 [1–5.5] 4 [1.5–7.5] 4 [1–9] .06
Days of intubation 1 [0.75–2.25] 2 [1–8.5] 4 [1–28] 21 [3.5–52.5] .004
Oxygen at 36 weeks 5 (28%) 23 (51%) 12 (57%) 9 (69%) .12
Postnatal steroid use 0 9 (20%) 10 (48%) 7 (54%) .001
Inotrope use 1 (6%) 12 (27%) 11 (52%) 9 (69%) <.001
Patent ductus arteriosus 5 (28%) 14 (31%) 11 (52%) 9 (69%) .04
Total parenteral nutrition 10.5 [9–16.5] 16 [12.5–26.5] 29 [14.5–47] 25 [10–36] .004
Chorioamnionitis 5 (28%) 19 (42%) 9 (45%) 4 (31%) .61
Confirmed sepsis 2 (11%) 10 (22%) 9 (43%) 8 (62%) .007
Necrotizing enterocolitis 0 2 (4%) 3 (14%) 2 (15%) .19
Note:—Data are mean (SD), number (%), or median [lower-upper quartile].