Table 2:

ANCOVA pos hoc and AUC results of the WMTI metrics of each corpus callosum ROI and the FA skeleton

	ROI	NC (n = 15)	aMCI (n = 12)	AD (n = 14)	NC vs aMCI		aMCI vs AD		NC vs AD
	ROI	Mean ± SD	Mean ± SD	Mean ± SD	P Value	AUC	P Value	AUC	P Value	AUC
AWF	Genu	0.35 ± 0.03	0.33 ± 0.03	0.32 ± 0.05	.25	0.75	.43	0.67	.01^{^a,^b}	0.78
	Body	0.35 ± 0.03	0.33 ± 0.03	0.32 ± 0.04	.33	0.71	.35	0.65	.01^{^a,^b}	0.76
	Splenium	0.41 ± 0.03	0.39 ± 0.03	0.35 ± 0.06	.36	0.69	.02^a	0.79	<.01^{^c,^b}	0.88
	Skeleton	0.39 ± 0.02	0.38 ± 0.02	0.36 ± 0.04	.93	0.64	.01^{^a,^b}	0.84	<.01^{^d,^b}	0.83
D_axon	Genu	1.09 ± 0.06	1.09 ± 0.05	1.10 ± 0.09	1.00	0.66	.88	0.53	.88	0.53
	Body	1.22 ± 0.10	1.18 ± 0.07	1.19 ± 0.10	.65	0.64	.98	0.54	.75	0.56
	Splenium	1.20 ± 0.09	1.17 ± 0.05	1.15 ± 0.12	.82	0.63	.62	0.71	.25	0.71
	Skeleton	0.96 ± 0.05	0.95 ± 0.04	0.93 ± 0.07	1.00	0.66	.57	0.77	.49	0.68
D_e,‖	Genu	2.90 ± 0.13	3.06 ± 0.07	3.10 ± 0.17	.01^{^a,^b}	0.86	.57	0.60	<.01^{^c,^b}	0.85
	Body	2.83 ± 0.11	3.01 ± 0.10	2.99 ± 0.15	<.01^{^d,^b}	0.89	.93	0.54	<.01^{^d,^b}	0.79
	Splenium	2.79 ± 0.11	2.93 ± 0.11	2.95 ± 0.11	.01^{^a,^b}	0.82	.78	0.57	<.01^{^d,^b}	0.88
	Skeleton	2.30 ± 0.07	2.39 ± 0.04	2.40 ± 0.07	<.01^{^c,^b}	0.95	.88	0.53	<.01^{^c,^b}	0.92
D_e,⊥	Genu	1.33 ± 0.11	1.52 ± 0.16	1.58 ± 0.27	.01^{^a,^b}	0.91	.30	0.64	<.01^{^c,^b}	0.91
	Body	1.43 ± 0.10	1.58 ± 0.12	1.62 ± 0.22	.03^a	0.88	.49	0.63	<.01^{^c,^b}	0.80
	Splenium	1.15 ± 0.10	1.29 ± 0.12	1.43 ± 0.25	.06	0.87	<.01^{^d,^b}	0.77	<.01^{^c,^b}	0.93
	Skeleton	1.06 ± 0.07	1.15 ± 0.07	1.20 ± 0.16	.04^a	0.89	.06	0.77	<.0^{^c,^b}	0.89

Note:—AUC indicates area under the receiver operating characteristic curve.
↵a P < .05.
↵b P values indicate that the difference remains significant after applying a Bonferroni correction for multiple ROI comparisons.
↵c P < .001.
↵d P < .01.