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Table 1: Demographic information
Characteristic Female Control Subjects (n = 16) Female Patients (n = 16) Male Control Subjects (n = 16^a) Male Patients (n = 16)
Mean age, y (SD) 42.25 (9.4) 42.38 (9.5) 41.81 (9.6) 40.94 (8.9)
Mean education, y (SD) 16.44 (1.3) 15.00 (2.6) 16.81 (3.7) 16.3 (2.9)
Median EDSS (range) NA 2 (1–3.5) NA 1.5 (1–6)
Median disease duration (range) NA 8 (1–24) NA 6.5 (1–29)
Disease phenotype NA 16 RR NA 14 RR/2 SP
Mean cognitive task scores (SD) 
     Symbol Digit Modalities Test 64.50 (10.1) 59.38 (9.0) 61.55 (12.3) 59.88 (8.5)
     Paced Auditory Serial Addition Test 51.81 (8.6) 49.44 (9.8) 51.73 (7.5) 54.25 (6.4)
     California Verbal Learning Test 53.69 (10.7) 56.25 (12.1) 54.09 (12.9) 49.06 (11.4)
     Brief Visuospatial Memory Test–Revised 26.56 (3.9) 25.31 (4.7) 27.18 (5.1) 26.81 (5.2)
     Controlled Word Association Test 44.44 (9.3) 47.13 (10.9) 45.36 (7.1) 45.94 (8.3)
Motion characteristics, mm 
     Mean (SD) 0.275 (0.10) 0.290 (0.09) 0.309 (0.11) 0.254 (0.07)
     Peak (SD) 0.629 (0.36) 0.724 (0.45) 0.742 (0.37) 0.555 (0.30)
Note:—RR indicates relapse-remitting; SP, secondary-progressive; NA, not applicable; EDSS, Expanded Disability Status Scale.
↵a n = 11 for male control subjects on all cognitive tasks.