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3T MRI signs of HS detected by visual or quantification analysisa
MRI Visual AnalysisVolumetryRelaxometryVolumetry + Relaxometry
MTLE-HS (125/203; 62%)119/125 (95%)103/125 (82%)124/125 (99%)
MTLE-NL (78/203; 38%)10/78 (13%)15/78 (19%)22/78 (28%)
Concordance with EEG laterality95% had concordant EEG* and 5% discordant94% had concordant EEG** and 6% discordant
  • Note:—NL, indicates normal MRI.
  • ↵a First column shows the frequency of HS signs detected by visual analysis. The other columns show the percentages of HS signs detected by quantification of hippocampal volume (“Volumetry”) and T2 MRI signal (“Relaxometry”) alone (second and third columns, respectively) or when considered together (fourth column). In the last line, for each technique the concordance with the laterality of the seizure focus is described as defined by ictal and interictal scalp EEG.
  • ↵* Excluding the 9 patients and ** the 12 patients with bilateral non-lateralizing EEG.