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Table 1:

Demographic and clinical features of the 65 participants

FeatureHealthy Pediatric Controls (n = 26)Pediatric RRMS (n = 26)APOMS RRMS (n = 13)
Female (No.)18 (69.2%)16 (61.5%)8 (61.5%)
Age at enrollment (yr) (mean) (SD)15.4 (3.6)16.2 (2.5)20.3 (2.9)
     Range (yr)(8.94–18.61)(9.36–18.08)(18.24–23.76)
Age at first attack (mean) (SD) (yr)N/A12.3 (3.9)13.9 (3.6)
Disease duration (mean) (SD) (yr)N/A3.9 (4.4)6.5 (3.7)
     Range (yr)(0.67–13.34)(4.01–10.42)
EDSS (median, IQR)N/A1.5 (1.0, 2.5)1.5 (1.0, 2.0)
Medications used (No.) (%)N/A
     None9 (34.7)2 (15.4)
     IFN11 (42.3)7 (53.9)
     GA4 (15.4)2 (15.4)
     Other2 (7.7)2 (15.4)
  • Note:—N/A indicates not applicable; EDSS, Expanded Disability Status Scale; IQR, interquartile range; IFN, interferon; GA, glatiramer acetate.