1naresh
Array
(
    [urn:ac.highwire.org:guest:identity] => Array
        (
            [runtime-id] => urn:ac.highwire.org:guest:identity
            [type] => guest
            [service-id] => ajnr-ac.highwire.org
            [access-type] => Controlled
            [privilege] => Array
                (
                    [urn:ac.highwire.org:guest:privilege] => Array
                        (
                            [runtime-id] => urn:ac.highwire.org:guest:privilege
                            [type] => privilege-set
                            [privilege-set] => GUEST
                        )

                )

            [credentials] => Array
                (
                    [method] => guest
                )

        )

)
1naresh
Array
(
    [urn:ac.highwire.org:guest:identity] => Array
        (
            [runtime-id] => urn:ac.highwire.org:guest:identity
            [type] => guest
            [service-id] => ajnr-ac.highwire.org
            [access-type] => Controlled
            [privilege] => Array
                (
                    [urn:ac.highwire.org:guest:privilege] => Array
                        (
                            [runtime-id] => urn:ac.highwire.org:guest:privilege
                            [type] => privilege-set
                            [privilege-set] => GUEST
                        )

                )

            [credentials] => Array
                (
                    [method] => guest
                )

        )

)


Table 3: 
MRI white matter signal abnormality (≥3 mm in size) characteristics of non-familial healthy control subjects and the healthy relatives of patients with multiple sclerosis
Non-Familial HCs (n = 82)Healthy Relatives of Patients With MS (n = 68)P Value
Subjects with WM SAs, n (%)21 (25.6)20 (29.4).603
    Subjects with WM JC SAs, n (%)4 (4.9)7 (10.3).205
    Subjects with WM PVL SAs, n (%)7 (8.5)13 (19.1).058
    Subjects with WM IT SAs, n (%)0 (0)1 (1.5).271
    Subjects with DWM SAs, n (%)20 (24.4)17 (25.0).931
Subjects with ≥9 WM SAs, n (%)4 (4.9)6 (8.8).335
WM-SAN, mean (SD), median1.5 (4.7) 02.1 (5.1) 0.527
    WM JC SAN, mean (SD), median0.06 (0.3) 00.19 (0.7) 0.198
    WM PVL SAN, mean (SD), median0.32 (1.8) 00.40 (1.2) 0.061
    WM IT SAN mean (SD) median0.0 (0) 00.01 (0.1) 0.272
    WM DWM SAN, mean (SD), median1.1 (3.0) 01.5 (3.9) 0.838
WM-SAV, mean (SD), median166.1 (892.0)230.4 (736.8).480
DAWM-SAV,a mean (SD), median675.3 (554.7)866.2 (669.3).054
WM-SAV + DAWM-SAV, mean (SD), median842.3 (1079.7)1096.5 (1026.6).024
  • Note:—SAs indicates signal abnormalities; SAN, signal abnormality number; JC, juxtacortical, PVL, periventricular; IT, infratentorial; DWM, deep white matter; SAV, signal abnormality volume.
  • Differences between the groups were compared by means of the χ2 test or Mann-Whitney U test.
  • The SAV is expressed in millimeters cubed (mm3).
  • ↵a DAWM calculation was not related to the size of the hyperintensities.