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Table 3: Descriptive statistics of orbital lesion ADC across the largest source datasets (ADC in units of 10⁻³ mm²/s)
All Lesions (n = 183) Sepahdari et al¹³ (n = 50) Politi et al¹⁷ (n = 90) Razek et al¹⁶ (n = 43)
Benign lesion ADC (mean, 95% CI) 1.42 ± 0.41 (1.34–1.51) 1.36 ± 0.41 (1.22–1.51) 1.39 ± 0.42 (1.25–1.54) 1.53 ± 0.35 (1.37–1.67)
Malignant lesion ADC (mean, 95% CI) 0.90 ± 0.37 (0.83–0.98) 1.02 ± 0.42 (0.80–1.24) 0.88 ± 0.36 (0.79–0.98) 0.80 ± 0.34 (0.65–0.95)
Lymphoma ADC (mean, 95% CI) 0.67 ± 0.09 (0.64–0.69) 0.69 ± 0.16 (0.58–0.86)^a 0.67 ± 0.07 (0.60–0.75) 0.67 ± 0.07 (0.60–0.73)^a
Inflammatory lesion ADC (mean, 95% CI) 1.40 ± 0.31 (1.30–1.50) 1.42 ± 0.37 (1.24–1.60) 1.45 ± 0.26 (1.29–1.60) 1.24 ± 0.13 (1.18–1.33)^a
Area under ROC curve (95% CI) 0.84 (0.79–0.90) 0.74 (0.58–0.89) 0.86 (0.79–0.94) 0.95 (0.87–1.0)
↵a The 25th-75th percentile range was reported due to a sample size too small to assume normal distribution.