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Table 2: 
Demographic and clinical characteristics of non-familial healthy control subjects and the healthy relatives of patients with multiple sclerosis
Non-Familial HCs (n = 82)Healthy Relatives of Patients with MS (n = 68)P Value
Age, y, mean (SD) median39.8 (14.3) 4339.5 (16.6) 43.917
Sex, female n (%)57 (69.5)45 (66.2).663
Race/ethnicity, n (%).180
    White64 (78.1)62 (91.2)
    Black12 (14.6)4 (5.9)
    Other6 (7.3)2 (2.9)
Vascular risk factors, n (%)
    Heart disease8 (9.8)13 (19.1).085
    Smoking22 (27.5)19 (27.9).979
    Hypertension17 (20.7)15 (22.1).442
    Obesity n (%)a.582
    BMI <18.52 (2.4)2 (2.9)
    BMI 18.5–24.934 (41.5)25 (36.8)
    BMI 25–29.926 (31.7)17 (25.0)
    BMI >3013 (15.8)18 (26.5)
Autoimmune diseases, n (%)
    Systemic lupus erythematosus00NA
    Rheumatoid disorder1 (1.2)2 (2.9).474
    Psoriasis01 (1.5).279
    Diabetes mellitus type 11 (1.2)0.352
Migraine, n (%)10 (12.2)13 (19.1).282
  • Note:—BMI indicates body mass index.
  • BMI <18.5 represents underweight, BMI 18.5–24.9 represents normal weight, BMI 25–29.9 represents overweight, and BMI >30 represents obesity. The differences between the groups were compared by means of the Student t test or the χ2 test.
  • ↵a Data missing for 13 subjects.