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Table 2:

Volumetric comparison of radiotracers in MRI for GBM

GBM (n=10)TV (45.4 ± 26.5 cm3)aCEV (21.6 ± 14.3 cm3)b
62Cu-ATSM (8.2 ± 14.0 cm3)P = .002P = .002
FDG (11.0 ± 12.0 cm3)P = .002P = .006
MET (38.0 ± 19.0 cm3)P = .56P = .06
  • Note:—The mean tumor volume (TV) and contrast-enhanced volume (CEV) were compared with the active volume of 62Cu-ATSM (T/B cutoff threshold ≥1.8), FDG (T/B cutoff threshold of ≥1.5), and MET (T/B cutoff threshold of ≥1.3). P values < .05 were considered to indicate statistical significance.

  • a TV was measured as a completely covered contrast-enhanced region with necrotic and cystic components.

  • b CEV was measured as a contrast-enhanced region without necrotic and cystic components on T1-weighted MRI with Gd-DTPA.