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Table 1: Demographics and clinical features
Group
HC ALS
n 18 20
M/F 10/8 10/10
Mean age, y (SD) 60 (10.5) 61.5 (9.1)
Disease duration, mean y (SD) n/a 2.6 (2.7)
Upper limbs onset n/a 10
Lower limbs onset n/a 10
ALSFRS-R, mean (SD) n/a 36.2 (8.7)
48-ALSFRS-R/months of disease duration, mean (SD) n/a 0.64 (0.7)
UMN score, mean (SD) n/a 7.1 (3.9)
FrSBe, mean (SD) n/a 102.3 (18.5)
Note:—n/a indicates not applicable; SD, standard deviation.

	Group
	HC	ALS
n	18	20
M/F	10/8	10/10
Mean age, y (SD)	60 (10.5)	61.5 (9.1)
Disease duration, mean y (SD)	n/a	2.6 (2.7)
Upper limbs onset	n/a	10
Lower limbs onset	n/a	10
ALSFRS-R, mean (SD)	n/a	36.2 (8.7)
48-ALSFRS-R/months of disease duration, mean (SD)	n/a	0.64 (0.7)
UMN score, mean (SD)	n/a	7.1 (3.9)
FrSBe, mean (SD)	n/a	102.3 (18.5)