Table 1:

Details of included serial MRI studies

MRI Modality		Population	Timing of MRI (wk)	Main Findings
Structural conventional	Dyet et al⁸	119 Infants <30 wks	Serial	Abnormal outcome^{^a} at 18 mos was related to major destructive lesions, DEHSI, cerebellar hemorrhage, and posthemorrhagic ventricular dilation
	Miller et al³⁹	89 Infants <34 wks	32 + 37	Abnormal outcome at 18 mos^{^b} was related to severity of WM injury, ventriculomegaly, and intraventricular hemorrhage on first (RR, 5.6) and second (RR, 5.3) MRIs
	Tam et al⁴⁰	131 Infants <34 wks	32 + 37	Abnormal neurologic examination findings at 4.8 yrs were related to large and small cerebellar hemorrhage; OR for small hemorrhage was 5.0
DTI	Drobyshevsky et al⁷⁰	24 Infants <32 wks	30 + 36	PDI^{^b} at 24 mos correlated to FA of the PLIC at 30 wks (r = 0.55), faster increase of FA/wk in internal capsule (r = −0.63), and occipital WM (r = −0.59)
	Glass et al⁷¹	9 Infants <34 wks	33 + 38	FA of the optic radiation was correlated with visual-evoked-potential amplitude (r = 0.7) at 10.5 mos
Volumetric	Dubois et al⁸¹	45 Infants <36 wks	32 + 41	Functional assessment at term was associated with inner cortical surface and sulcation index
	Kapellou et al⁸² Rathbone et al⁸³	119 Infants <30 wks	Serial	Growth of the cortical surface area was related to neurodevelopmental outcome^{^a} at 24 mos and full-scale IQ at 6 yrs

Note:—RR indicates relative risk; OR, odds ratio; PDI, Psychomotor Development Index.
↵a Griffiths Mental Developmental Scales.
↵b Bayley Scales of Infant Development.