1naresh
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HC (n = 110) MS (n = 285) RRMS (n = 210) PMS (n = 75) P Value Age (y), mean (SD) median 47.0 (12.9) 50 46.9 (8.2) 48 0.965 46.1 (8.5) 46 49.2 (6.5) 50 .006* Sex, female, n (%) 76 (69.1) 206 (72.3) 0.329 149 (70.9) 57 (78) .496 Disease duration (y), mean (SD) median NA 14.4 (9.1) 13 13.2 (8.8) 12 17.9 (9.2) 18 <.001* EDSS, mean (SD) median NA 3.4 (1.9) 3.0 2.6 (1.5) 2.5 5.4 (1.5) 6.0 <.001* T2-LV, mean (SD) median 0.3 (1.2) 0 13.5 (16.1) 7.3 <.001* 11.0 (13.5) 6.7 20.4 (20.4) 13.2 .001* T1-LV, mean (SD) median 0 3.3 (6.5) 1.0 NA 2.7 (6.1) 0.8 5.1 (7.2) 1.7 .037* T1-Gd-LV mean (SD) median NA 0.05 (0.02) 0 NA 0.06 (0.4) 0 0.01 (0.02) 0 .046*
Note:—EDSS indicates Expanded Disability Status Scale; LV, lesion volume; NA, not available; SD, standard deviation.
Statistical analysis among groups was performed with the Student t test, test, the Mann-Whitney U test and the χ2 test. All P values were corrected for multiple comparisons with use of Benjamini-Hochberg correction.
The volumes are expressed in milliliters.
↵* indicates significant P values (P < .05) after correction.