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Table 1: 
Summary of metabolites/compounds detected by each type of MRS and findings
Type of MRSMetabolites/Compounds DetectedSummary of Findings
19F MRSFluorine 19 nucleus
Fluorinated drugs (including SSRIs)		Used to study pharmacokinetics of fluoxetine and fluvoxamine31
31P MRSPhosphomonoesters
Phosphodiesters
Inorganic phosphate
Phosphocreatine
α-, β-, and γ-nucleoside triphosphate		Membrane phospholipid and energy metabolism abnormalities in frontal and temporal lobes of patients with bipolar disorder36
Lower phosphomonoester levels for patients with euthymic bipolar disorder37
Increased phosphomonoester and decreased ATP levels in frontal lobes of unipolar depressed patients38
Proton MRSGlx
GABA
NAA
Cr+PCr
Cho
mIns		See Table 2
  • Note:—APT indicates adenosine triphosphate; SSRI, selective serotonin reuptake inhibitor.