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Table 2: Selected ProFit-quantified metabolite ratios (mean ± SD) calculated from predominantly the occipital and medial frontal gray matter regions and the prefrontal WM (left) of 9 patients with OSA and 11 healthy controls
Metabolite Ratios Occipital Gray Matter Medial Frontal Gray Matter Left Frontal White Matter
OSA HC OSA HC OSA HC
tNAA 1.793 ± 0.39^{^a} 2.158 ± 0.54 0.949 ± 0.26^{^a} 1.268 ± 0.17 1.190 ± 0.28 1.323 ± 0.31
Glx 1.637 ± 0.41 1.451 ± 0.58 1.531 ± 0.48 1.289 ± 0.49 1.658 ± 0.40 1.661 ± 0.45
tCho 0.192 ± 0.05^{^a} 0.252 ± 0.09 0.317 ± 0.08 0.346 ± 0.09 0.236 ± 0.05^{^a} 0.346 ± 0.06
NAA 1.510 ± 0.42 1.893 ± 0.43 0.744 ± 0.30^{^a} 1.052 ± 0.25 0.904 ± 0.26 0.950 ± 0.28
mIns 0.634 ± 0.28 0.493 ± 0.21 1.792 ± 0.65 1.536 ± 0.42 1.545 ± 0.31 1.496 ± 0.39
Tau 0.140 ± 0.0^{^a} 0.421 ± 0.20 0.627 ± 0.24 0.906 ± 0.37 0.341 ± 0.12^{^a} 0.826 ± 0.38
sI 0.038 ± 0.01^{^a} 0.052 ± 0.01 0.099 ± 0.04 0.117 ± 0.05 0.073 ± 0.02 0.102 ± 0.03
GPC 0.160 ± 06 0.169 ± 0.07 0.181 ± 0.10 0.210 ± 0.09 0.170 ± 0.10 0.135 ± 0.09
PCh 0.064 ± 0.02^{^a} 0.125 ± 0.05 0.079 ± 0.02 0.151 ± 0.04 0.228 ± 0.09 0.076 ± 0.048
Note:—HC indicates healthy controls; GPC, glycerylphosphocholine; PCh, phosphocholine; sI, scyllo-Inositol; Tau, taurine.
↵a P < .0.5.