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Table 4: 
Regional analysis of FDG uptakea
RegionFDG Uptake Ratio
HCMCIADF2, 27Sig.
MeanSDMeanSDMeanSD
Temporal lobe
    Hippocampus R.615.036.576.069.583.0241.9NS
    Hippocampus L.619b.030.573.069.517c.0766.6<.01
    Parahippocampal and ambient gyri R.597.052.569.055.580.036.90NS
    Parahippocampal and ambient gyri L.612.044.576.038.545.0674.5<.05
    Anterior TL lateral part R.692.064.639.064.672.0512.1NS
    Anterior TL lateral part L.733b.052.672c.062.661.0634.4<.05
    Anterior TL medial part R.564.052.532.065.572.0491.4NS
    Anterior TL medial part L.590.033.539.055.557.0632.9NS
    Posterior TL R.853.048.826.049.814.0581.5NS
    Posterior TL L.875b.048.831.068.789c.0784.2<.05
Insula and cingulate gyri
    Insula R.799.040.766.048.773.0301.9NS
    Insula L.789.048.767.049.764.043.82NS
    Anterior cingulate R.865.039.850.051.886.0261.8NS
    Anterior cingulate L.867.034.843.051.869.0301.3NS
    Posterior cingulate R1.06.0481.03.0741.01.0272.2NS
    Posterior cingulate L1.05b.0471.01.068.969c.0385.9<.01
Frontal lobe
    Middle frontal gyrus R1.07b,d.060.993c.074.988c.0445.9<.01
    Middle frontal gyrus L1.07b.048.999.073.983c.0485.6<.01
    Medial orbitofrontal R.865.033.832.075.859.0321.2NS
    Medial orbitofrontal L.854.032.798.064.827.0324.0<.05
    Subgenual anterior cingulate R.654.041.631.054.660.065.84NS
    Subgenual anterior cingulate L.665.044.623.079.665.0731.4NS
Parietal/occipital lobe
    Cuneus R.991.058.963.089.946.083.84NS
    Cuneus L.991.049.994.065.925.1142.3NS
    Superior parietal lobe R1.02b,d.033.956c.051.933c.04111.3<.001
    Superior parietal lobe L1.02b.038.974.067.913c.0577.9<.01
    Inferolateral parietal lobe R1.02b.057.962.069.918c.0616.2<.01
    Inferolateral parietal lobe L1.02b.036.945.083.884c.0798.8.001
Central structures
    Thalamus R.849b.063.791.088.760c.0354.2<.05
    Thalamus L.846b.060.808.087.762c.0513.4.05
    Caudate R.851.088.799.143.795.067.86NS
    Caudate L.844.104.817.104.785.040.97NS
    Putamen R1.06.0631.08.0941.10.074.75NS
    Putamen L1.06.0621.08.0851.08.059.41NS
  • Note:—HC indicates healthy controls; NS, not significant; Sig., Significance; R, right; L, left; TL, temporal load.
  • ↵a Superscript letters indicate significant pair-wise comparisons revealed by post hoc testing (Tamhane T2, P = .05).
  • ↵b Significantly different from AD.
  • ↵c Significantly different from HC.
  • ↵d Significantly different from MCI.