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Table 1: Basic descriptive statistics and neuropsychological scores^{^a}
HC MCI AD
Mean SD Mean SD Mean SD
Age (yr) 69.6^{^b} 5.5 74.1 6.4 77.8^{^c} 5.0
Sex (M/F) 3:8 9:2 5:3 
Years of education 13 3.2 13.5 4.1 11.5 3.2
MMSE score 29.6^{^b} 0.5 28.6 1.3 24.9^{^c} 2.8
APOE ϵ4 1/10 5/8 7/8 
TIV (cm³) 1700 160 1800 120 1800 210
Total ACE-R 94.6^{^b,^d} 4.3 88.7^{^b,^c} 6.1 73.3^{^c,^d} 7.9
ACE-R Memory 23.7^{^b,^d} 2.2 19.5^{^b,^c} 3.6 11.1^{^c,^d} 2.9
Category Fluency 100^{^b,^d} 12.6 77.8^{^b,^c} 17.5 55.1^{^c,^d} 15.4
ACE-R Attention 18^{^b} 0.0 17.8 0.4 16^{^c} 1.9
Note:—HC indicates healthy controls; APOE ϵ4 indicates the number of participants carrying at least 1 ϵ4 allele (APOE data were unavailable from 1 healthy control and 3 patients with MCI); MMSE, Mini-Mental State Examination; TIV, total intracranial volume.
↵a Superscript symbols indicate significant pair-wise comparisons revealed by post hoc testing (Tamhane T2, P = .05). There was a significant group difference for age, F(2, 27) = 4.5, P < .05; MMSE score, F(2, 27) = 20.2, P < .001; total ACE-R, F(2, 27) = 29.9, P < .001; ACE-R Memory, F(2, 27) = 42.2, P < .001; Category Fluency, F(2, 27) = 20.1, P < .001; ACE-R Attention, F(2, 27) = 11.4, P < .001.
↵b Significantly different from AD.
↵c Significantly different from HC.
↵d Significantly different from MCI.