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Table 2: Tract-based spatial statistics group analysis identifying WM tracts with significantly lower FA values in patients with cognitive impairment compared with patients without cognitive impairment
Total Voxels Significant Voxels % Significant
Middle cerebellar peduncle 2608 2068 79.3%
Corpus callosum 7044 6891 97.8%^{^a}
R corticospinal tract 134 72 53.7%
L corticospinal tract 208 154 74.0%
R medial lemniscus 174 158 90.8%
L medial lemniscus 209 171 81.8%
R cerebellar peduncle 476 331 69.5%
L cerebellar peduncle 414 294 71.0%
R cerebral peduncle 575 502 87.3%
L cerebral peduncle 600 415 69.2%
R internal capsule 2219 1728 77.9%
L internal capsule 1659 1308 78.8%
R corona radiata 3935 3267 83.0%
L corona radiata 3142 2486 79.1%
R posterior thalamic radiation 1086 1044 96.1%^{^a}
L posterior thalamic radiation 554 554 100.0%^{^a}
R sagittal stratum 652 636 97.5%^{^a}
L sagittal stratum 345 329 95.4%^{^a}
R external capsule 1115 993 89.1%
L external capsule 565 437 77.3%
R cingulum 526 397 75.5%
L cingulum 319 220 69.0%
R superior longitudinal fasciculus 1614 1363 84.4%
L superior longitudinal fasciculus 1338 840 62.8%
Note:—R indicates right; L, left.[br /]
↵a Regions with greater than 95% WM impingement.

	Total Voxels	Significant Voxels	% Significant
Middle cerebellar peduncle	2608	2068	79.3%
Corpus callosum	7044	6891	97.8%^{^a}
R corticospinal tract	134	72	53.7%
L corticospinal tract	208	154	74.0%
R medial lemniscus	174	158	90.8%
L medial lemniscus	209	171	81.8%
R cerebellar peduncle	476	331	69.5%
L cerebellar peduncle	414	294	71.0%
R cerebral peduncle	575	502	87.3%
L cerebral peduncle	600	415	69.2%
R internal capsule	2219	1728	77.9%
L internal capsule	1659	1308	78.8%
R corona radiata	3935	3267	83.0%
L corona radiata	3142	2486	79.1%
R posterior thalamic radiation	1086	1044	96.1%^{^a}
L posterior thalamic radiation	554	554	100.0%^{^a}
R sagittal stratum	652	636	97.5%^{^a}
L sagittal stratum	345	329	95.4%^{^a}
R external capsule	1115	993	89.1%
L external capsule	565	437	77.3%
R cingulum	526	397	75.5%
L cingulum	319	220	69.0%
R superior longitudinal fasciculus	1614	1363	84.4%
L superior longitudinal fasciculus	1338	840	62.8%