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Table 2: Neuroanatomic regions with reduced FA in CCS users relative to healthy controls
Anatomic Regions Laterality Talairach Coordinates (x, y, z)^{^a} Cluster Size (cm) Average FA P Values (Minimum)^{^b}
CCS Users Controls
Frontal region of the IFO R 67,154,68 136 0.533 0.564 .048
Temporo-occipital region of IFO R 54,95,77 389 0.452 0.499 .031
L 130,84,65 40 0.622 0.661 .042
123,66,72 38 0.477 0.549 .046
Superior corona radiata R 71,83,112 586 0.578 0.646 .031
Note:—L indicates left; R, right.
↵a All the coordinates are denoted by Montreal Neurological Institute space coordinates.
↵b P < .05, threshold-free cluster enhancement–corrected).

Anatomic Regions	Laterality	Talairach Coordinates (x, y, z)^{^a}	Cluster Size (cm)	Average FA		P Values (Minimum)^{^b}
Anatomic Regions	Laterality	Talairach Coordinates (x, y, z)^{^a}	Cluster Size (cm)	CCS Users	Controls	P Values (Minimum)^{^b}
Frontal region of the IFO	R	67,154,68	136	0.533	0.564	.048
Temporo-occipital region of IFO	R	54,95,77	389	0.452	0.499	.031
	L	130,84,65	40	0.622	0.661	.042
		123,66,72	38	0.477	0.549	.046
Superior corona radiata	R	71,83,112	586	0.578	0.646	.031