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Table 2: 
Detection of histologically confirmed brain tumors on MR images acquired after administration of 0.1-mmol/kg gadoteridol or 0.1-mmol/kg gadobutrol in 139 patients with 308 brain lesions subsequently confirmed at biopsy or surgery
Lesion DetectionReader 1Reader 2Reader 3
GadoteridolGadobutrolGadoteridolGadobutrolGadoteridolGadobutrol
No. patients with tumors detected at MRI133 (95.7%)135 (97.1%)137 (98.6%)136 (97.8%)136 (97.8%)132 (95.0%)
P value (95% CI of difference, %).317 (−4.2 to 1.4).564 (−1.7 to 3.2).046 (0.1 to 5.7)
No. tumors detected at MRI240 (77.9%)236 (76.6%)269 (87.3%)263 (85.4%)230 (74.7%)220 (71.4%)
P value (95% CI of difference, %)0.480 (−2.3 to 4.9)0.239 (−1.3 to 5.2)0.018 (0.6 to 5.9)