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Table 3: Group differences in diffusivity indices from volumes of interest (corrected for age, education, and histories of smoking)
Anatomic Region λ₁ (× 10⁻³mm²/s) (Mean) λ_⊥ (× 10⁻³mm²/s) (Mean)
Controls CCS P Value Controls CCS P Value
Right frontal part of IFO 1.37 ± 0.05 1.35 ± 0.05 .097 0.50 ± 0.05 0.54 ± 0.03 .001^{^a}
Right temporo-occipital part of IFO 1.43 ± 0.08 1.37 ± 0.06 .014^{^a} 0.40 ± 0.05 0.45 ± 0.04 .001^{^a}
Left temporo-occipital part of IFO 1.44 ± 0.07 1.40 ± 0.07 .027^{^a} 0.46 ± 0.05 0.51 ± 0.04 .000^{^a}
Right superior corona radiata 1.27 ± 0.07 1.22 ± 0.07 .018^{^a} 0.53 ± 0.05 0.56 ± 0.04 .011^{^a}
↵a P < .05.

Anatomic Region	λ₁ (× 10⁻³mm²/s) (Mean)			λ_⊥ (× 10⁻³mm²/s) (Mean)
Anatomic Region	Controls	CCS	P Value	Controls	CCS	P Value
Right frontal part of IFO	1.37 ± 0.05	1.35 ± 0.05	.097	0.50 ± 0.05	0.54 ± 0.03	.001^{^a}
Right temporo-occipital part of IFO	1.43 ± 0.08	1.37 ± 0.06	.014^{^a}	0.40 ± 0.05	0.45 ± 0.04	.001^{^a}
Left temporo-occipital part of IFO	1.44 ± 0.07	1.40 ± 0.07	.027^{^a}	0.46 ± 0.05	0.51 ± 0.04	.000^{^a}
Right superior corona radiata	1.27 ± 0.07	1.22 ± 0.07	.018^{^a}	0.53 ± 0.05	0.56 ± 0.04	.011^{^a}