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Table 3: Differences of clinical and imaging thresholds in patients receiving thrombolysis versus untreated patients
No Reperfusion Therapy IV and/or IA Therapy P Value
DWI 
    AUC ± SE for predicting poor outcome 0.935 ± 0.06 0.724 ± 0.05 .011
    90% Specificity for poor outcome (prognostic yield) (mL) >19.7 (42.3%) >51.8 (19.5%) .016^{^a}
    95% Specificity for poor outcome (prognostic yield) (mL) >20.5 (40.5%) >74.8 (16.1%) .007^{^a}
>30.6 (35.1%) >103.1 (10.4%) .003^{^a}
NIHSS score 
    AUC ± SE for predicting poor outcome 0.903 ± 0.06 0.827 ± 0.04 .314
    90% Specificity for poor outcome (prognostic yield) >12 (37.8%) >16 (23.0%) .142^{^a}
    95% Specificity for poor outcome (prognostic yield) >15 (27.0%) >19 (14.9%) .182^{^a}
    100% Specificity for poor outcome (prognostic yield) >17 (16.2%) >20 (9.2%) .414^{^a}
↵a P value for comparison among prognostic yields.