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Table 2: Association of abnormal WMHI and characteristics in 149 patients with fCCM^{^a}
fCCM Characteristic Abnormal WMHI (n = 23) Normal WMHI (n = 126) P Value
Sex (No.) (%) 
    Female 18 (78) 75 (60) .11
    Male 5 (22) 51 (40) 
Age (yr) (mean) (SD) 23 (41) 32 (16) .01
Headaches (No.) (%) 
    Yes 15 (65) 79 (64) 1.00
    No 8 (35) 45 (36) 
Seizures (No.) (%) 
    Yes 11 (48) 48 (39) .49
    No 12 (52) 76 (61) 
Thyroid (No.) (%) 
    Yes 3 (13) 9 (7) .40
    No 20 (87) 115 (93) 
Diabetes (No.) (%) 
    Yes 2 (9) 12 (10) 1.00
    No 21 (91) 112 (90) 
Hyperlipidemia (No.) (%) 
    Yes 7 (30) 17 (13) .06
    No 16 (70) 109 (87) 
Hypertension (No.) (%) 
    Yes 6 (26) 15 (12) .10
    No 17 (74) 109 (88) 
Modified Rankin Scale (No.) (%) 
    0 4 (17) 46 (37) .33
    1 10 (44) 37 (30) 
    2 7 (30) 27 (22) 
    3 2 (9) 11 (9) 
    4 0 (0) 2 (2) 
CCM lesions 
    Median (IQR) 29 (29) 11 (39) .08
    Mean (SD) 60 (122) 42 (96) 
Note:—IQR indicates interquartile range.
↵a Note that some numbers for characteristics do not add up to column totals due to missing data.