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Table 3: 
Clinical variables associated with radiation necrosis
Statistically SignificantNot Statistically Significant
>3 Chemotherapy agents (P = .03)Age, 2 years or younger (P = .11)
ATRT pathology (P = .03)Age, 3 years or younger (P = .34)
Sex (P = 1.0)
Gross total surgical resection (P = .77)
Medulloblastoma tumor pathology (P = .35)
Ependymoma tumor pathology (P = .15)
Germinomaa (P = .3)
Infratentorial tumor location (P = 1.0)
Pineal tumor locationa (P = .16)
Craniospinal radiation (P = .48)
Total radiation dose (P = .66)
  • Note:—ATRT indicates atypical teratoid rhabdoid tumor.
  • ↵a No pineal tumors or germinomas demonstrated radiation necrosis.