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Table 2:

ROC analysis: dichotomized favorable outcome (mRS ≤2)a

VariableAUCP Value95% CIOOPSensitivitySpecificity
Final infarct (mL)0.96<.0010.91–1.0029.191%88%
RAPID rCBV core0.86.0010.74–0.9610.485%78%
RAPID rCBF core0.81<.0010.68–0.935.673%72%
RAPID Tmax >4 sec0.80<.010.65–0.93146.673%67%
RAPID Tmax >6 sec0.77<.010.63–0.9281.977%72%
RAPID Tmax >8 sec0.76<.010.60–0.9153.177%72%
RAPID Tmax >10 sec0.74<.010.58–0.8926.673%72%
NCCT-ASPECTS0.72.010.57–0.879.568%68%
CBV-ASPECTS0.75.010.61–0.895.076%62%
CBF-ASPECTS0.72.020.57–0.875.058%66%
Clot burden score0.74.010.59–0.896.558%77%
Collateral scoreb.72.200.56–0.891.570%70%
  • Note:—OOP indicates optimal operating point, optimal cut-off from ROC analysis for the variable of interest.

  • a Results of ROC analysis relative to dichotomized favorable clinical outcome (90-day mRS ≤2). Performance indicated by ROC AUC in descending-order performance.

  • b Significant relationships were observed for all tested variables, with the exception of the CTA collateral score.