Table 2:

Metrics of rCBV estimation methods^{^a}

Method	RC (RC_L–RC_U)	wCV	tSD	bSD	wSD
A) Normalized rCBV (tumor)
2 (CTI)	1.78 (1.44–2.34)	0.31	0.96	0.71	0.64
3 (GV)	1.95 (1.57–2.57)	0.25	1.04	0.77	0.70
6 (NEI)	2.07 (1.67–2.73)	0.24	1.57	1.38	0.75
1 (UTI)	3.16 (2.55–4.16)	0.39	1.55	1.05	1.14
5 (MSD)	3.54 (2.86–4.66)	0.56	1.30	0.25	1.28
4 (PBC)	3.93 (3.17–5.18)	0.67	1.85	1.18	1.42
B) Standardized rCBV (tumor)
2 (CTI)	3869 (3121–5093)	0.18	3142	2814	1397
4 (PBC)	4020 (3243–5292)	0.20	3045	2677	1451
3 (GV)	4214 (3399–5547)	0.17	3163	2773	1521
1 (UTI)	4261 (3437–5609)	0.19	2958	2526	1538
5 (MSD)	4591 (3703–6043)	0.13	6437	6220	1658
6 (NEI)	5250 (4235–6911)	0.16	5732	5410	1895

Note:—ΔR2*(t) indicates methods for which the transverse relaxation time courses are computed from the signal time courses; UTI, integration of ΔR2*(t) with the trapezoid rule; CTI, integration of ΔR2*(t) with the trapezoid rule and correction for T1 and T2 extravasation effects; GV, γ-variate fit to ΔR2*(t); NEI, negative enhancement integral of S(t); MSD, maximum signal drop of S(t); PBC, postbolus baseline (recirculation) correction; RC_L, lower RC confidence interval; RC_U, upper RC confidence interval; tSD, total SD; bSD, between-subject SD; wSD, within-subject SD.
↵a Shown in A and B are the RC, upper and lower 95% CI for RC, wCV, and SDs (total, between, and within-subject) for nRCBV and sRCBV, respectively, in which methods are sorted in order of greatest repeatability, as determined by the RC for nRCBV or sRCBV.