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Table 1: Baseline group characteristics
Characteristic Microbleeds Absent P Value^{^a} Microbleeds Present P Value^{^b}
Lobar Microbleeds Only Mixed Lobar and Deep Gray/ Infratentorial Microbleeds Deep Gray/Infratentorial Microbleeds Only
    No. of subjects 407 163 29 27 
    Mean age (SD), y 72 (7.6) <.001^{^c} 74 (7.0) 77 (6.4) 77 (9.0) .06
    Sex, male/female 218:189 .15 100:63 17:12 14:13 .64
    Mean education (SD), y 16 (2.6) .24 16 (2.9) 16 (2.9) 16 (2.3) .78
    % with HTN 47 .28 46 72 67 .009^{^d}
    % with APOE4 43 .15 53 52 26 .03^{^d}
    % with APOE2 allele 7 >.99 6 7 19 .06
    % with NL 26 .14 20 10 33 .10
    % with MCI 61 .80 61 79 56 .33
    % with AD 12 .18 18 10 11 .41
Note:—HTN indicates hypertension; MCI, mild cognitive impairment; NL, normal cognitive function; SD, standard deviation.
↵a P values compare baseline variables between those without microbleeds and those with microbleeds (combining the 3 groups with different types of microbleeds).
↵b P values compare baseline variables among the 3 groups with microbleeds.
↵c Significance according to the Wilcoxon rank sum test.
↵d Significance according to the χ² test.