1naresh
Array
(
    [urn:ac.highwire.org:guest:identity] => Array
        (
            [runtime-id] => urn:ac.highwire.org:guest:identity
            [type] => guest
            [service-id] => ajnr-ac.highwire.org
            [access-type] => Controlled
            [privilege] => Array
                (
                    [urn:ac.highwire.org:guest:privilege] => Array
                        (
                            [runtime-id] => urn:ac.highwire.org:guest:privilege
                            [type] => privilege-set
                            [privilege-set] => GUEST
                        )

                )

            [credentials] => Array
                (
                    [method] => guest
                )

        )

)
1naresh
Array
(
    [urn:ac.highwire.org:guest:identity] => Array
        (
            [runtime-id] => urn:ac.highwire.org:guest:identity
            [type] => guest
            [service-id] => ajnr-ac.highwire.org
            [access-type] => Controlled
            [privilege] => Array
                (
                    [urn:ac.highwire.org:guest:privilege] => Array
                        (
                            [runtime-id] => urn:ac.highwire.org:guest:privilege
                            [type] => privilege-set
                            [privilege-set] => GUEST
                        )

                )

            [credentials] => Array
                (
                    [method] => guest
                )

        )

)


Table 2: 
Most up-regulated canonical pathways, determined by IPA
Canonical Biologic PathwayNo. of Genes Up-RegulatedGenesNo. of Genes Down-RegulatedGene(s)
Dendritic cell maturation25CD80, CD83, CD86, CD1C, COL10A1, COL1A1, COL1A2, FCGR1B, FCGR2A, HLA-A, HLA-DMA, HLA-DMB, HLA-DOB, HLA-DQA1, HLA-DRA, HLA-DRB1, HLA-DRB5, IL15, IL1B, IL1RL2, IL1RN, PIK3CG, PIK3R5, PLCB2, TREM23CREB5, PLCB4, PLCL1
Role of NFAT in regulation of the immune response22BLNK, BTK, CD80, CD86, FCER1A, FCGR1B, FCGR2A, FOS, GNG2, HLA-DMA, HLA-DMB, HLA-DOB, HLA-DQA1, HLA-DRA, HLA-DRB1, HLA-DRB5, LCP2, LYN, PIK3CG, PIK3R5, PLCB2, SYK2PLCB4, GNAO1
Antigen-presentation pathway12CD74, HLA-A, HLA-DMA, HLA-DMB, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQB2, HLA-DRA, HLA-DRB1, HLA-DRB50NA
Altered T-cell and B-cell signaling in rheumatoid arthritis17CCL21, CD80, CD86, HLA-DMA, HLA-DMB, HLA-DOB, HLA-DQA1, HLA-DRA, HLA-DRB1, HLA-DRB5, IL15, IL1B, IL1RN, SPP1, TLR1, TLR8, TNFSF13B0NA
Atherosclerosis signaling19ALOX5, CCL2, CCR2, COL10A1, COL1A1, COL1A2, CXCR4, IL8, IL1B, IL1RN, LYZ, MSR1, PDGFB, PDGFC, PDGFD, PLA2G7, PLA2R1, SELE, VCAM11RBP4
  • Note:—NA indicates not applicable; NFAT, nuclear factor of activated T cells.