1naresh
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Outcome No. of Studies OR (95% CI) Prevalence Asymptomatic Prevalence Symptomatic P Valuea I2 (%) Annular fissure 6 1.79 (0.97–3.31) 11.3% (9.0%–14.2%) 20.1% (17.7%–22.8%) .06 59 High-intensity zone 4 2.10 (0.73–6.02) 9.5% (6.7%–13.4%) 10.4% (8.0%–13.4%) .17 72 Central spinal canal stenosis 2 20.58 (0.05–798.77) 14.0% (10.4%–18.6%) 59.5% (54.9%–63.9%) .32 94 Disc bulge 3 7.54 (1.28–44.56) 5.9% (3.8%–8.9%) 43.2% (38.2%–48.2%) .03 90 Disc degeneration 12 2.24 (1.21–4.15) 34.4% (31.5%–37.5%) 57.4% (54.8%–59.8%) .01 89 Disc extrusion 4 4.38 (1.98–9.68) 1.8% (0.1%–3.7%) 7.1% (5.4%–9.4%) <.01 0 Disc protrusion 9 2.65 (1.52–4.62) 19.1% (16.5%–22.3%) 42.2% (39.3%–45.1%) .00 62 Modic changes 5 1.62 (0.48–5.41) 12.1% (9.6%–15.2%) 23.2% (21.7%–27.3%) .43 65 Modic 1 changes 2 4.01 (1.10–14.55) 3.2% (0.7%–9.4%) 6.7% (4.2%–10.4%) .04 0 Spondylolisthesis 4 1.59 (0.78–3.24) 3.2% (1.8%–5.8%) 6.2% (4.4%–8.7%) .20 0 Spondylolysis 2 5.06 (1.65–15.53) 1.8% (0.0%–5.3%) 9.4% (6.6%–12.4%) <.01 0
↵a P values are computed from the meta-analysis of ORs. Prevalence data are provided for reference but are not meant for statistical comparison.