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Clinical variables describing the total population, the low-risk cohort, and the excluded patientsa
Total Cohort Low-Risk Cohort Excluded P Valueb No. of patients (%) 51 39 (76.5) 12 (23.5) GA (weeks, days) (median) (range) 27 4/7 (25 0/7–31 4/7) 27 4/7 (25 5/7–30) 28 1/7 (25 0/7–31 4/7) NS Female (No.) (%) 29 (56.9) 19 (48.7) 10 (83) <.05 Weight (g) (median) (range) 889 (517–1590) 900 (560–1485) 727.5 (517–1590) NS Small for GA (weight <10th percentile) (No.) (%) 12 (23.5) 8 (20.5) 4 (33.3) NS Multiple births (No.) (%) 12 (23.5) 6 (15.4) 6 (50) <.05 Chorioamnionitis (No.) (%) 21 (41.2) 16 (41.0) 5 (41.7) NS Antenatal steroids (No.) (%) 45 (88.2) 34 (87.2) 11 (91.7) NS All BPD/severe BPD (No.) (%) 26 (51.0)/9 (17.6) 17 (43.6)/5 (12.8) 9 (75.0)/4 (33.3) NS Postnatal steroids (No.) (%) 7 (13.7) 2 (5.1) 5 (41.7) <.05 Treated patent ductus arteriosus (No.) (%) 25 (49.0) 17 (43.6) 8 (66.7) NS Early-onset sepsis (No.) (%) 13 (25.5) 11 (28.2) 2 (16.7) NS Late-onset sepsis (No.) (%) 17 (33.3) 13 (33.3) 4 (33.3) NS Necrotizing enterocolitis (No.) (%) 2 (3.9) 0 (0) 2 (16.7) NS Treated retinopathy of prematurity (No.) (%) 3 (5.9) 1 (2.6) 2 (16.7) NS Death (No.) (%) 2 (3.9) 0 (0) 2 (16.7) NS 6-Mo MDI (median) (range) 98 (74–118) 98 (86–118) 93 (74–102) <.05 6-Mo PDI (median) (range) 88 (49–111) 88 (62–111) 78.5 (49–88) <.05 18-Mo MDI (median) (range) 93 (65–127) 93 (65–127) 87 (79–101) NS 18-Mo PDI (median) (range) 83 (49–103) 84 (55–103) 71 (49–95) <.05
Note:—MDI indicates mental developmental index; PDI, psychomotor developmental index; BPD, bronchopulmonary dysplasia; NS, nonsignificant.
↵a Bronchopulmonary dysplasia: O2 supplementation for 28 days. Severe BPD: respiratory support at 36 weeks of GA. Necrotizing enterocolitis: Bell stage >2.
↵b Between low-risk cohort and excluded patients.