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Table 2: Radiologic characteristics of patients with or without cSS
Type of MBs No. of Patients (%) P Value
Total Any cSS No cSS
No. of patients 347 12 335 
Lobar MBs 
    Frontal 69 (19.9%) 7 (58.3%) 62 (18.5%) .003
    Temporal 65 (18.7%) 8 (66.7%) 57 (17.0%) <.001
    Parietal 78 (22.5%) 7 (58.3%) 71 (21.2%) .007
    Occipital 63 (18.2%) 7 (58.3%) 56 (16.7%) .002
Deep MBs 
    Thalamoganglionic 62 (17.9%) 3 (25.0%) 59 (17.6%) .456
    Brain stem 32 (9.2%) 3 (25.0%) 29 (8.7%) .088
    Cerebellum 48 (13.8%) 3 (25.0%) 45 (13.4%) .222
Topographic distribution of MBs 
    Strictly lobar 71 (20.5%) 6 (50.0%) 65 (19.4%) .020
    Strictly deep 10 (2.9%) 0 (0%) 10 (3.0%) 1.00
    Mixed 79 (22.8%) 5 (41.7%) 74 (22.1%) .154
    No MBs 187 (53.9%) 1 (8.3%) 186 (55.5%) .002
Lacunar infarcts 71 (20.5%) 6 (50.0%) 65 (19.4%) .020
WMH (mean)^{^a} 1.5 ± 0.8 1.9 ± 0.8 1.4 ± 0.8 .053
    0 32 (9.2%) 0 (0%) 32 (9.6%) 
    1 166 (47.8%) 4 (33.3%) 162 (48.4%) 
    2 107 (30.8%) 5 (41.7%) 102 (30.4%) 
    3 42 (12.1%) 3 (25.0%) 39 (11.6%) 
Note:—WMH indicates white matter hyperintensities.
↵a WMH were graded according to the scale of Fazekas et al¹⁷: 0, absent; 1, punctate; 2, early confluent; and 3, confluent.