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Table 2: Coefficients of variance of volumetric MRI measurements^{^a}
SyMRI (40 Participants) SyMRI (20 Patients with MS) SyMRI (20 Controls) SyMRI (5 Controls) SPM (5 Controls) FreeSurfer (5 Controls) FSL (5 Controls)
Brain volume 0.30 0.35 0.25 0.14 0.29 0.21 0.18
Gray matter volume 1.4 1.2 1.6 0.64 0.81 0.78 0.25
White matter volume 1.8 1.6 2.0 0.81 0.68 0.70 0.28
Intracranial volume 0.26 0.28 0.24 0.12 0.17 0.15 –
Brain parenchymal fraction 0.23 0.25 0.21 0.14 0.17 0.20 –
Gray matter fraction 1.4 1.2 1.6 0.56 0.78 0.64 –
White matter fraction 1.9 1.7 2.1 0.96 0.79 0.67 –
↵a All values represent the CoV in percentages. Volume is expressed in milliliters.

	SyMRI (40 Participants)	SyMRI (20 Patients with MS)	SyMRI (20 Controls)	SyMRI (5 Controls)	SPM (5 Controls)	FreeSurfer (5 Controls)	FSL (5 Controls)
Brain volume	0.30	0.35	0.25	0.14	0.29	0.21	0.18
Gray matter volume	1.4	1.2	1.6	0.64	0.81	0.78	0.25
White matter volume	1.8	1.6	2.0	0.81	0.68	0.70	0.28
Intracranial volume	0.26	0.28	0.24	0.12	0.17	0.15	–
Brain parenchymal fraction	0.23	0.25	0.21	0.14	0.17	0.20	–
Gray matter fraction	1.4	1.2	1.6	0.56	0.78	0.64	–
White matter fraction	1.9	1.7	2.1	0.96	0.79	0.67	–