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Table 5: Intergroup differences of the AD and RD values that contributed to the altered MD values^{^a}
T2DM (n = 58) Healthy Controls (n = 58) F P
Superior rPF_WM 
    AD, ×10⁻⁵ mm²/s 111.06 ± 6.52 105.23 ± 4.25 31.431 <.001
    RD, ×10⁻⁵ mm²/s 93.28 ± 6.41 87.75 ± 4.49 28.488 <.001
Middle rPF_WM 
    AD, ×10⁻⁵ mm²/s 113.59 ± 6.04 108.52 ± 3.48 31.472 <.001
    RD, ×10⁻⁵ mm²/s 90.12 ± 6.39 85.27 ± 3.53 27.982 <.001
Inferior rPF_WM 
    AD, ×10⁻⁵ mm²/s 116.85 ± 5.98 112.19 ± 5.53 18.548 <.001
    RD, ×10⁻⁵ mm²/s 84.53 ± 5.95 81.24 ± 4.38 10.752 .001
lPF_WM 
    AD, ×10⁻⁵ mm²/s 121.75 ± 10.54 114.50 ± 6.62 19.725 <.001
    RD, ×10⁻⁵ mm²/s 107.47 ± 11.40 98.84 ± 7.44 23.252 <.001
rST_WM 
    AD, ×10⁻⁵ mm²/s 127.10 ± 10.59 119.03 ± 6.38 22.413 <.001
    RD, ×10⁻⁵ mm²/s 102.70 ± 10.25 94.47 ± 5.85 25.394 <.001
Splenium of CC 
    AD, ×10⁻⁵ mm²/s 269.21 ± 20.44 255.20 ± 24.27 9.865 .002
    RD, ×10⁻⁵ mm²/s 152.25 ± 32.11 127.36 ± 32.84 15.805 <.001
lEC 
    AD, ×10⁻⁵ mm²/s 122.54 ± 7.42 117.14 ± 4.84 21.495 <.001
    RD, ×10⁻⁵ mm²/s 92.85 ± 8.70 86.36 ± 6.14 22.007 <.001
Pons 
    AD, ×10⁻⁵ mm²/s 222.11 ± 27.07 201.58 ± 26.15 18.416 <.001
    RD, ×10⁻⁵ mm²/s 177.25 ± 27.60 157.84 ± 24.38 17.237 <.001
Note:—lPF_WM indicates left prefrontal white matter; rST_WM, right superior temporal white matter.
↵a Data are presented as mean ± SD. The intergroup comparisons were performed with ANCOVA adjusted for age, sex, and years of education.