1naresh
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ROI Parameter Tissue Typea All Tissue Types Combined (n = 31)b GBM (n = 17)c Metastasis (n = 8)c LGG (n = 6) ST Mean 1639 ± 247 (v MET P ≤ .05) 1324 ± 273 (v LGG P ≤ .05) 1600 ± 197 1558 ± 271 (v CW P < .0063)d T1 SD 133 ± 50 116 ± 63 120 ± 26 126 ± 49 (v CW P < .0063)d Skewness 0.01 ± 0.66 0.38 ± 0.56 0.16 ± 0.52 0.12 ± 0.61 Kurtosis 3.06 ± 0.96 3.23 ± 0.58 3.26 ± 1.11 3.14 ± 0.90 ST Mean 138 ± 22 (v MET P ≤ .05) 105 ± 27 (v LGG P < .0042)d 172 ± 53 137 ± 37 (v CW P < .0063)d T2 SD 21 ± 9 17 ± 9 22 ± 12 20 ± 9 (v CW P < .0063)d Skewness 0.77 ± 1.43 (v LGG P ≤ .05) 0.67 ± 0.97 −0.28 ± 0.68 0.54 ± 1.25 Kurtosis 6.38 ± 8.61 5.49 ± 6.54 2.88 ± 0.61 5.47 ± 7.19 PW Mean 1578 ± 331 (v LGG P < .0042)d 1382 ± 188 (v LGG P ≤ .05) 1066 ± 218 1429 ± 338 (v CW P < .0063)d T1 SD 124 ± 59 (v LGG, MET P ≤ .05) 75 ± 27 73 ± 15 101 ± 52 (v CW P < .0063)d Skewness −0.06 ± 0.44 (v LGG P ≤ .05) −0.10 ± 0.39 (v LGG P ≤ .05) 0.54 ± 0.56 0.04 ± 0.50 Kurtosis 2.73 ± 0.81 2.84 ± 0.53 3.12 ± 0.97 2.83 ± 0.77 (v CW P ≤ .05) PW Mean 140 ± 27 (v LGG P ≤ .05) 119 ± 27 (v LGG P ≤ .05) 102 ± 43 127 ± 33 (v CW P < .0063) T2 SD 17 ± 7 (v LGG, MET P ≤ .05) 12 ± 7 10 ± 3 14 ± 7 (v CW P < .0063) Skewness 0.39 ± 1.51 (v LGG P ≤ .05) 0.39 ± 0.85 (v LGG P ≤ .05) 0.71 ± 0.53 0.45 ± 1.20 Kurtosis 5.68 ± 11.82 4.99 ± 2.84 3.45 ± 1.40 5.07 ± 8.80 CW Mean 927 ± 133 911 ± 39 873 ± 61 912 ± 104 T1 SD 40 ± 11 44 ± 12 36 ± 10 40 ± 11 Skewness 0.27 ± 0.51 0.45 ± 0.55 0.13 ± 0.69 0.29 ± 0.55 Kurtosis 3.22 ± 1.13 3.09 ± 0.57 3.54 ± 1.32 3.25 ± 1.04 CW Mean 69 ± 9 72 ± 6 72 ± 17 70 ± 11 T2 SD 5 ± 2 5 ± 1 6 ± 3 5 ± 2 Skewness 0.20 ± 1.60 0.27 ± 0.95 0.58 ± 0.95 0.31 ± 1.33 Kurtosis 4.85 ± 7.07 3.96 ± 2.07 3.82 ± 1.73 4.41 ± 5.32
Note:—v indicates versus (when compared to).
↵a When comparing tumor types by rank sum tests, P values < .0042 (0.05/12) were statistically significant after Bonferroni correction. P values labeled as P ≤ .05 have unadjusted P values ≤ .05 but are not statistically significant after Bonferroni correction.
↵b When comparing tumor tissue vs CW by signed rank tests, P values < .0063 (0.05/8) were statistically significant after Bonferroni correction.
↵c For solid tumor analysis for GBMs (n = 16) and for METs (n = 7) (see “ROI Analysis” in “Materials and Methods” for further details).
↵d P value statistically significant after Bonferroni correction.