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Table 2: Individual MRI measurements in PD, MSA-P, and PSP compared with controls in different structures
PD MSA-P PSP
FA MD R2* FA MD R2* FA MD R2*
Striatal and related structures 
    PUT ↑↑^{^a} ↑ 
    CN 
    GP ↑↑↑^{^a} ↑ ↑ ↑ 
Midbrain structures 
    antSN ↓ ↑ ↑↑ ↑
    postSN ↓↓ ↑ ↑↑ ↓ ↑ ↑↑↑↑^{^a} ↑↑
    RN ↑↑^{^a} ↓ ↑ ↑ ↑↑^{^a}
    STN ↓↓^{^a} ↑ ↑↑↑^{^a} ↑
Limbic structures 
    Hipp ↓ ↑↑↑↑^{^a} ↓
    AM ↓ ↓ ↑↑ 
Cerebellar structures 
    DN ↓ ↑↑^{^a} 
    CB ↓↓ ↑↑↑^{^a} ↓↓^{^a} ↑↑^{^a} 
    SCP ↓↓↓↓^{^a} ↑↑↑↑^{^a} 
    MCP ↓ ↑↑↑^{^a} ↓↓↓^{^a} ↑↑^{^a} 
Note:—antSN indicates anterior substantia nigra; postSN, posterior substantia nigra; Hipp, hippocampus; AM, amygdala; CB, cerebellum; DN, dentate nucleus; GP, globus pallidus; MCP, middle cerebellar peduncle; SCP, superior cerebellar peduncle.
↵a Statistical significance after Bonferroni correction (P < .0038, considering 13 independent tests). Upward arrows indicate increased MRI measures compared with controls, and downward arrows indicate decreased MRI measures compared with controls. ↑ represents P < .05, ↑↑ represents P < .01, ↑↑↑ represents P < .001, and ↑↑↑↑ represents P <0 .0001.

	PD			MSA-P			PSP
	FA	MD	R2*	FA	MD	R2*	FA	MD	R2*
Striatal and related structures
PUT					↑↑^{^a}			↑
CN
GP					↑↑↑^{^a}	↑	↑	↑
Midbrain structures
antSN				↓		↑		↑↑	↑
postSN	↓↓	↑	↑↑	↓		↑		↑↑↑↑^{^a}	↑↑
RN			↑↑^{^a}	↓	↑			↑	↑↑^{^a}
STN				↓↓^{^a}	↑	↑↑↑^{^a}			↑
Limbic structures
Hipp							↓	↑↑↑↑^{^a}	↓
AM				↓			↓	↑↑
Cerebellar structures
DN							↓	↑↑^{^a}
CB				↓↓	↑↑↑^{^a}		↓↓^{^a}	↑↑^{^a}
SCP							↓↓↓↓^{^a}	↑↑↑↑^{^a}
MCP				↓	↑↑↑^{^a}	↓↓↓^{^a}		↑↑^{^a}