1naresh
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Variables Arthrogryposis Pb No (n = 8) Yes (n = 4) Decreased brain volume 6 (75.0%) 4 (100.0%) .515 Grade of brain volume decrease Mild 1 (20.0%) 0 (0.0%) .876 Moderate/severe 4 (80.0%) 3 (100.0%) Degree of cerebral damage .394 Absent 1 (12.5%) 0 (0.0%) Mild 2 (25.0%) 0 (0.0%) Moderate 2 (25.0%) 0 (0.0%) Severe 3 (37.5%) 4 (100.0%) Symmetry 6 (75.0%) 3 (75.0%) >.999 Cortical development abnormalities Pachygyria 3 (37.5%) 3 (75.0%) .545 Polymicrogyria 2 (25.0%) 0 (0.0%) .515 Simplified gyral pattern 4 (50.0%) 3 (75.0%) .576 Corpus callosum >.999 Normal 2 (25.0%) 0 (0.0%) Hypogenesis 5 (62.5%) 3 (75.0%) Hypoplasia 1 (12.5%) 1 (25.0%) Cortical and subcortical junction calcifications 7 (85.5%) 4 (100.0%) >.999 Basal ganglia calcifications 3 (37.5%) 3 (75.0%) .545 Periventricular calcifications 0 (0.0%) 3 (75.0%) .018c Brain stem calcifications 1 (12.5%) 3 (75.0%) .067 Cerebellum calcifications 0 (0.0%) 2 (50.0%) .091 Cerebellum or brain stem hypoplasia 2 (25.0%) 4 (100.0%) .061 Increased cisterna magna 8 (100.0%) 4 (100.0%) – Delayed myelination 5 (50.0%) 4 (100.0%) .208