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Table 3:

Measurement of TV, sensitivity, specificity, PPV, NPV, YI, and AUC of ADCmin values, rADC, rCBVmax, cMRI, DWI + DSC-PWI, and cMRI+ DWI + DSC-PWI for assessing the IDH status of grade II and III astrocytomas

TVSensitivity (%)Specificity (%)PPV (%)NPV (%)YIAUC (95% CI)
ADCmin1.0176.9282.6191.2060.500.600.87 (0.71–0.96)
rADC1.6084.6273.9188.3067.300.590.84 (0.68–0.94)
rCBVmax2.35100.0060.8785.60100.000.610.82 (0.66–0.93)
cMRI88.2452.0088.5044.300.400.78 (0.63–0.89)
DWI + DSC-PWI100.0065.2287.00100.000.650.88 (0.54–0.84)
cMRI+ DWI + DWI-PWI92.3191.3096.1083.600.840.92 (0.78–0.98)
  • Note:—TV indicates threshold values; PPV, positive predictive value; NPV, negative predictive value; YI, Youden Index; AUC, area under the curve.