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Summary of the meta-analytic pooled proportions for nondiagnostic results, inconclusive results, and malignancy on CNB
No. of Studies Total No. of Cases Summary Estimate Trim-and-Fill Estimate
Pooled Proportion (95% CI) P Value for Heterogeneity^{^a} I^2b No. of Missing Studies Adjusted Pooled Proportion (95% CI)
Nondiagnostic results 6 1836 1.8% (0.4%–3.2%) <.01 94.6% 2 0.8% (−0.8%–2.5%)
Inconclusive results 6 1836 25.1% (15.4%–34.9%) <.01 95.8% 0 
Malignancy 6 1836 18.9% (8.4%–29.5%) <.01 98.3% 1 15.6% (4.4%–26.8%)
↵a P value by the Cochran Q method to test the heterogeneity of the pooled data, with P < .05 indicating substantial heterogeneity.
b Higgins index for heterogeneity (0%–40%, might not be important; 30%–60%, may represent moderate heterogeneity; 50%–90%, may represent substantial heterogeneity; 75%–100%, may represent considerable heterogeneity).