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Table 1: 
Patient clinical characteristics and imaging metrics
Entire CohortPatients with 12-Month Follow-Up
No. of subjects4028
Sex (F/M)33/724/4
Age (mean) (yr)42.9 ± 12.542.1 ± 13.1
EDSS0 (mean)3.4 ± 1.93.6 ± 2
EDSS12 m (mean)4.2 ± 2.3
MS type (RR/SP/unknown/PP)32/2/5/123/1/3/1
Disease duration (mean) (yr)8.0 ± 6.46.9 ± 4.5
T2 lesion load (mean) (mL)21.3 ± 22.823.3 ± 26.0
CST FA (mean)0.44 ± 0.030.44 ± 0.03
CST MD (mean)0.94 ± 0.060.93 ± 0.06
CST λ⊥ (mean)0.70 ± 0.060.70 ± 0.06
CST (mean)1.41 ± 0.071.40 ± 0.07
CST MK (mean)1.17 ± 0.061.17 ± 0.06
CST K⊥ (mean)1.60 ± 0.151.60 ± 0.14
CST K‖ (mean)0.96 ± 0.050.97 ± 0.05
  • Note:—RR indicates relapsing-remitting MS; SP, secondary-progressive MS; PP, primary-progressive MS.