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Table 3:

Proportion of participants in whom MRI findings worsened or improved during a 12-week perioda

MRI Findings/Subjective ChangeControlsSubjects with LBP
WorsenedImprovedWorsened or ImprovedWorsenedImprovedWorsened or Improved
Disc degeneration1/100/101/102/200/202/20
= 10%= 0%= 10%= 10%= 0%= 10%
Disc signal intensity1/100/101/102/200/202/20
= 10%= 0%= 10%= 10%= 0%= 10%
Disc height1/100/101/100/200/200/20
= 10%= 0%= 10%= 0%= 0%= 0%
HIZ0/104/104/105/203/208/20
= 0%= 40%= 40%= 25%= 15%= 40%
Annular fissure0/101/101/102/203/205/20
= 0%= 10%= 10%= 10%= 15%= 25%
Modic changes1/101/102/101/202/203/20
= 10%= 10%= 20%= 5%= 10%= 15%
Disc herniation0/103/103/107/206/2013/20
= 0%= 30%= 30%= 35%= 30%= 65%
Facet joint arthropathy0/100/100/100/200/200/20
= 0%= 0%= 0%= 0%= 0%= 0%
Central canal stenosis0/100/100/100/200/200/20
= 0%= 0%= 0%= 0%= 0%= 0%
Spondylolisthesis or retrolisthesis0/100/100/100/200/200/20
= 0%= 0%= 0%= 0%= 0%= 0%
Edema0/101/101/100/200/200/20
= 0%= 10%= 10%= 0%= 0%= 0%
Nerve root compromise0/100/100/102/201/203/20
= 0%= 0%= 0%= 20%= 10%= 15%
  • a If a particular MRI finding both improved and worsened at different follow-up time points (compared with baseline), we reported the change at or closest to the 12-week time point.