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Table 1: 
Adult and pediatric cohorts by histology and genetic status
Adult (This Cohort, n = 28)Pediatric (Perreault et al. 201414) (n = 47)
Median age (range) (yr)39.0 (33.4–41.3)8.2 (0.9–33.9)
Male/female1.5:1.02.4:1.0
Genetic entity (No.) (%)
    SHH19 (67.9%)13 (27.7%)
    WNT4 (14.2%)4 (8.4%)
    Group 45 (17.9%)17 (36.2%)
    Group 30 (0.0%)13 (27.7%)
Histologic entity (No.) (%)
    Classic13 (46.4%)31 (66.0%)
    Desmoplastic/nodular15 (53.6%)4 (8.5%)
    Large cell anaplastic0 (0.0%)10 (21.3%)
    Other subgroups0 (0.0%)2 (4.2%)
  • Note:—SHH indicates sonic hedgehog–activated medulloblastoma; WNT, wingless-activated medulloblastoma.